Archives for posts with tag: FET

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In this (almost) 2WW, insanity has been my friend.  And I think I mentioned before – as has google.

In my trawls I found this really interesting table that I found really helpful for anyone going through this process.  It breaks it all down step by step on what (hopefully) happens with a 5 day (blastocyst) transfer:

  • -1 dpt    Embryo is growing and developing
  • 0 dpt   Embryo is now a blastocyst
  • 1 dpt   Blastocyst hatches out of shell on this day
  • 2 dpt   Blastocyst attaches to a site on the uterine lining
  • 3 dpt   Implantation begins, as the blastocyst begins to bury in the lining
  • 4 dpt   Implantation process continues and morula buries deeper in the lining
  • 5 dpt   Morula is completely implanted in the lining and has placenta cells and fetal cells
  • 6 dpt   Placenta cells begin to secret HCG in the blood
  • 7 dpt   More HCG is produced as fetus develops
  • 8 dpt   More HCG is produced as fetus develops
  • 9 dpt   HCG levels are now high enough to be immediately detected on HPT.

I’ve had no particular symptoms.  I’ve been analysing even twinge in my belly and every small pain in my back.  But I’ve had no real pains, my boobs haven’t felt any different etc.  I was feeling bloated up until last Thursday, but that eased off.  I convinced myself the treatment hadn’t worked.  I decided to do the test a day early because I was supposed to take it on Monday morning (today), but I wanted to have Sunday to get over the upset if it came back negative.  I knew I wouldn’t want to face work.

But…..turns out I was wrong.  It was positive!  Instantly.  No waiting 2 minutes.

As soon as hubby woke up I told him.  His big boyish grin reassured me he was happy.

After work today, I went and bought 2 more tests.  I still can’t believe it.  I took one straight away when I got in, which again confirmed the positive result.  I will take another one tomorrow.  Just to be sure……

I am now booked for a scan on 24 April.  I’m not sure I will believe it until after that.  I am still yet to be able to say the words out loud either.  I am pregnant.  It might be a while before I can.

 

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Well that’s it.  Two blastocysts moved in today.  I hope they like it enough to stick around.

I left home with plenty of time.  As I had to go to Harley Street in central London, I opted for train and tube rather than driving (hubby’s experience of doing that at the egg collection stage was not a good one!).  I thought that would be less stressful and just easier in general.

However, they can be unreliable – hence allowing myself plenty of time.  So, when I got to my local station to find a packed platform and not enough space on the first train…..it was fine.  I was happy to wait for the next one.  When there was a delay on the tube because of a broken down train…..again it was fine…..actually did me a favour preventing me from being too early!

Knowing I had to have a full bladder for this (I hate that part), I emptied my bladder before I left home.  I had a drink with me for the journey.  I was more than half an hour early – but felt comfortable…..by the time my appointment was due – I’d be ready.  Speaking to the receptionist they had my name on the list (phew!) but said there was a slight delay.  They had had a fire alarm earlier on in the day.  At this point I started getting a little concerned….would my bladder hold out.  ‘Don’t drink any more’ the receptionist said ‘just to be sure’. Great!

15 minutes after my appointment time (not too bad I thought), I was taken in.  After getting in the normal garb (those sexy hospital gowns) I was then scanned (externally) to make sure my bladder was sufficiently full.  The nurse looked at the screen, ‘Oh you are more than ready!’….hmmm yes thanks…….I know that already……..I feel like my bladder is about to burst!

After all the polite introductions, the embryologist confirmed both embryos survived the thaw. What a relief! Then before I knew it, I was lying back on the bed, legs akimbo and in stirrups with the bed god knows how high in the air.  A giant light shining on my minnie, just to be sure everyone got a good view!  Sadly, after being on this road for so long, I was actually beyond caring.

I’ve posted before about the actual process followed, and this was exactly the same.  All in all, in lasted 5 minutes.

After that, I pee’d for England, got dressed and headed home again.  A nice leisurely pace, all the time in the world.

So here we go, the start of the infamous 2 week wait (2WW).  On 10th April we’ll find out.  Come on little beans……stick…….hang on for your lives………please like your new home!

 

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In my previous post, I mentioned that we needed to make a decision…..a choice…..one egg or two for the FET.

I am all booked in for Wednesday at 2pm.

First of all – I would like to curse the internet.  Providing so much information (sometimes conflicting) that my head is ready to burst and full of worst case scenarios.  I know this sounds hypocritical, considering I am writing a blog online, but right now – I feel like ignorance would be bliss.  But, that’s just not my style.  I research, research, research.  I like to make informed decisions.

Up until now, the only decision we have had to make so far is that we want a family.  All the other decisions have pretty much been made by the doctors and we have gone along with them.  All part of the process.

But this ball is firmly back in our court.

From pretty early on, I was always inclined to go for 2 eggs (if that was an option).  Because I am over 35, it is an option (in my area, they will not do multiple eggs if under 35) and we have enough good quality eggs.  The main thoughts behind this were: we don’t mind having twins, in fact I quite like the idea albeit am petrified how hard it will be; I want to improve my chances of this being successful first time (surely 2 eggs have more chance??); and research has highlighted the risk that not all eggs survive the thawing process.

There are negatives in that; there are likely to be more pregnancy complications with twins; as I understand it I am at a higher risk of miscarriage because of my PCOS; if we were lucky enough for two sticky beans, they would likely need to be born prematurely which is a risk for them; and should something happen to one – there is a risk I lose both.

Then, at my last scan, the doctor said I should go for one.  The eggs are high quality and so she thinks its a given I will fall pregnant with twins.  Whilst I like her confidence….her main concern was the complications during pregnancy.  She also confirmed, if we went for one egg, and that did not survive the thaw, another one would be done immediately on the day, so there would be no further delays (another concern).

When I called the clinic to then make my appointment for the FET – I said that very thing because they already had the paperwork stating two eggs were to be transferred.  The woman was very kind and talked me through a few points; apparently alot of doctors advise against twin pregnancies due to the difficulties, but according to my notes, she said there was not reason to believe I would have any problems; this clinic’s success rate is 40 – 50% with one egg and 50 – 60% with two eggs; and in reality, as a clinic, they only advise against two eggs if there is a medical condition which means it really should be avoided, or we really don’t want twins.

This has swayed me back to going with two eggs again.

Now, I am bricking it.  A new concern that has entered my head.  What if the eggs do stick (yay) and then split? Forming 2 sets of identical twins??? Can my body cope with that? Would they survive??  In the past some of hubby’s family have joked around saying hubby was actually a twin, but the other twin didn’t survive.  I don’t think it is true…..I need to speak to my mother in law!

Has anyone else in this position actually been scared of success in this?  This is something that we have wanted for so long, but will change everything.  Are my worries normal?  I am dreading failure and a negative test at the end of the 2WW, but I am braced for it.  Or are all these random thoughts because of these hormone drugs???

Anyway – one step at a time.  4 days to go, and 2 eggs will be transferred.  Lets do this.

My scan confirmed today that the Progynova medication has worked. My lining is ‘nice and thick’ – the apparent technical term.

My instructions now are to stop the Suprecur injections, continue with the Progynova tablets (1, 3 times a day) and start with the progesterone pessaries (2 a day, morning and night).  And, tomorrow I need to call the embryologist and book the transfer. The doctor said at a guess, that would be Wednesday next week. 6 days time. Wow. Seems real now.

She also advised me to only do 1 egg and not 2 as we were originally planning. She said all the eggs were top quality and a twin pregnancy could lead to more complications. But, she said it was ultimately down to us……oh the decisions.  I don’t mind having twins, I actually like the idea, but I don’t want to put myself in a position of something going wrong. We need to decide before I make the call in the morning!

I am continuing to struggle with the emotional roller coaster this week. This week was particularly stressful with hubby going away for a course and the the attacks on London yesterday (with a family member working in Parliament stress levels were very high until we got confirmation he was ok).

So here is hoping for a better week next week! For us and the country!

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I say a week, its been 5 days now, so just shy of a week.

So I’ve been injecting Suprecur (50 units) once a day now.  I am glad that has reduced down, but my belly is feeling more tender now.  Initially the injections didn’t hurt, but now it seems to be that little bit more painful each time.  I’ll be glad to see the back of them!

The progynova is a small tablet – similar to the ones I used to take when on the contraceptive pill.  Nice and easy to swallow.  I need to take one 3 times a day.  But I have a shocking memory – so this is proving quite difficult for me!  I now have alarms set for everything as I simply don’t remember anything anymore.  This is not a side effect of any medication – more a side effect of being in my family.  We are all like it – I am sure it is inherited!!

Side effects – well – I can tell the progynova is a hormone treatment.  I am just hoping it is helping to thicken my lining as it is supposed to – making the rest all worth it.

Compared to all the other medications – it is this that has sent me a little crazy.  Mood swings – not quite, but boy has it made my emotions be all over the place!! Definitely feel like I am yo-yoing.  It is hard work for me – never mind my hubby/family around me.  Sorry peeps!

One other thing I have noticed is my psoraisis.  I struggle with it at times anyway – normally stress related, and it has recently flared up in more places than usual.  I am not sure if that is because of having a new bathroom fitted and being stressed about that (but I don’t feel stressed) or whether it is linked to the medication.  I’ll be monitoring that one!

Five more days to go until my next scan.  I hope my lining is as thick as it needs to be so I can book in the FET!  Eeeeek!  Nerves are kicking in now!

 

Today was a scan day.  Time to see if my body has been responding to the medication as it is supposed to.

Phew! It has.  My lining is thin as it is supposed to and my ovaries are ‘quiet’. The technical terms apparently!

So, I now start taking Progynova (Oestradiol Valerate) – 1 tablet (2mg), 3 times a day and 1 Suprecur injection a day (still 50 units).

Symptom wise – everything pretty much has remained the same.

I’m booked in for another scan in 10/11 days time. Hopefully my body responds to this next step as it is supposed to as well!

 

Aunt Flo arrived this morning!  Only a few days beyond the 28 days.  That’s a shocker!

So, this means I will start Suprecur tonight.

Taking these injections every 12 hours will have its limitations.  I tend to be a homely person anyway, but the invites of going places seem to come along like buses.  I don’t get invited anywhere for ages and then suddenly they all come at once!  We were invited to go to Cornwall (a 5 hour drive from here in London) this weekend to see some friends, but I said that doing so would mean I would need to take enough injections with me – ‘just in  case’ I came on. And then we’d need to make sure we could get back to our friend’s house at appropriate times (call me weird but I don’t fancy injecting myself in a public toilet in a pub somewhere! – plus I need a sharps bin).  So, we declined.  I actually think hubby was a little relieved to not have to do so much travelling this weekend with a bad back!

Then this evening I was invited at the last minute to a friend’s house.  An impromptu get together – always the best kind.  But for my first injection – I didn’t really want to be round someone’s house in their bathroom hiding away.

Tomorrow I have to travel to Wales for a business meeting.  At least I know I can be in my own hotel room for the injections which will make it a bit easier.  Still not ideal but never mind!

Anyway – back to the topic at hand – I’ll start the injections tonight.  I’ve chosen to do them at 8 o’clock as that will work for me both in the morning and evening most days when I am at work as usual.  A fellow blogger also kindly advised me to keep hydrated and drink lots while taking these – and so I fully intend to follow that advice!

Suddenly we are another step closer to the FET!

 

After my appointment this morning, this is what the doctors have decided for me. Having my Frozen Embryo Transfer on a Hormone Replacement Therapy.

This means, day 1 of my cycle is when I start Buserelin injections. I have to inject myself twice a day, 12 hours apart.  2 weeks after that I’ll have a scan to confirm that I have ‘down regulated’ (basically my ovaries have shut down). As long as the medication has worked, then I will start taking Oestradiol Valorate (oral tablets) 3 times a day while still continuing with the injections.  2 weeks after that I will then be scanned again to check that my lining is at least 8mm thick. If all looks good, I stop the injections, continue the Oestradiol Valorate and start using the progesterone pessaries (those bad boys again! Ergh!).  At that point I’ll be booked in for the actual transfer within 3 to 7 days.

So all in all, that process will be 5 weeks at most. I am ‘due’ to start my cycle in 2 weeks. Whilst I doubt my body will work to time…..this means in 7 weeks time I could be having the transfer.  In 9 weeks then testing to see if it worked.  This makes it seem much more real now….I so hope this works, but am trying to be realistic that it might not.  We may not be lucky enough to have a sticky bean…..or problems could happen during the thaw out.

Because of my age, they have agreed to try transferring 2 embryos. If neither of these work, I’ll do future attempts one at a time I think. I only have 5, so I feel like I have to be tactical to maximise chances of a successful bubba.

In other news, I didn’t get the job I went for last week. But I got really positive feedback from the guy that interviewed me, so that has helped me boost my confidence to go for others when they arise. 

So it’s been a good week. Hopefully there will be more to come!

Oh the joys of treatment on the NHS. I am so paranoid about my age knowing the older you are the less chance there is of a successful pregnancy, so all of these (unnecessary) delays are raising my stress levels.

I went and had my scan. Everything is fine and looking normal. So let’s get you booked in for the Frozen Embryo Transfer (FET). You need to have an appointment with the nurse to talk you through the process and sign consent forms.

Perfect….or so I thought. 1st of bloody March! Excuse my language. Yet more delays. Just for an ‘educational’ chat and sign papers! Why the hell didn’t they get me doing that whilst waiting for this cycle. Come on! No effective time management at all.

I think I must have one of those faces that shows what I’m thinking…..because I then suddenly got an earlier slot on 10 Feb.  But that will still be too late for this cycle. Aaaaaaaaarrrrggghhhhh.

And then, yesterday I see all over the news Beyoncé is pregnant with twins. How quickly did that make the green eyed monster awaken in me?! I hate that. I don’t want to be that person.

So roll on next Friday. I just want a chance!

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So after the whole feeling sorry for myself, I entered the new year feeling more positive and optimistic. I was also determined to try and take some control back of my life, and stop ‘waiting’ around for my life to change.

I worked through Christmas and New Year as I take the first few weeks of January off most years. The only exception this year was that we didn’t go on holiday, but I still had the time off work.  As much as I felt like I was hibernating, I now realise that it was a much needed break and was also quite productive.

The first day of my holidays, I made contact with the architect we previously met in Cyprus.  She is now investigating whether we can use the land we own to build our home on.  This is going to be a long, drawn out process, but at least I started the ball rolling!

I applied for a new job.  Somehow, I got through the sift and I have an interview next week.  Safe to say I am bricking it right now, but it has been a welcome distraction and given me something else to think about.  I am not holding my breath in actually getting the job, as it is promotion for me, but I am looking at even getting an interview as a step in the right direction and getting some practice in for future jobs!

I also had a mate who is a builder come in and quote for fitting a new bathroom.  It is all now bought and sitting in the garage.  Hopefully he will be coming to fit it all in the next week or so!  The bathroom is actually older than I am, so this is long overdue and I can’t wait to get under my new rain water shower head (I lead a sheltered life!!).

And lastly, I was due on on Tuesday last week.  For a change, this month, I was only a few days late and my period started yesterday.  Which means tomorrow I can phone the clinic and get the ball rolling again for my FET (Frozen Embryo Transfer) this month.  I’ve been reading up on it, and I don’t know whether the doctor will want to work with my natural cycle or whether I will be given blocker medication to prevent me ovulating.  Either way, I’ve been trying to calculate when this might happen.  Maybe a few weeks. Which may work out perfectly as I have 2 more weeks annual leave booked for the last 2 weeks of February.

I feel like I am at a bus stop right now.  Nothing has come along for ages, and now they are all arriving at once.  I am feeling excited, overwhelmed and panicked all at the same time.  For all of the above!

Regardless, I am in a much better head space now and hope I can keep hold of my current Positive Mental Attitude.  It will help me deal with whatever comes my way – success or not.